Tryptophan

Tryptophan

SCHEMBL3857030

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nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.70
▸ MAPT P10636 3/20 0.70
▸ KMT2A Q03164 3/20 0.70
▸ LMNA P02545 2/20 0.70
▸ TSHR P16473 2/20 0.70
▸ BLM P54132 2/20 0.70
▸ PMP22 Q01453 2/20 0.70
▸ MEN1 O00255 2/20 0.70
▸ MPO P05164 1/20 0.70
▸ HIF1A Q16665 1/20 0.70
▸ APAF1 O14727 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ HTR2A P28223 3/20 0.52
▸ HTR1A P08908 2/20 0.51
▸ HTR2C P28335 2/20 0.51
▸ SLC6A4 P31645 2/20 0.51
▸ HTR7 P34969 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL2060360 0.96 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL4400705 0.96 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27147785 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL6268677 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL12497478 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL11217425 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL5481922 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL537140 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL537138 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL12497474 0.93 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592160-B2 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2009-09-22 — — US disclosed
US-7241606-B2 α-Isomaltosylglucosaccharide synthase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-07-10 — — US disclosed
US-7192746-B2 α-Isomaltosyltransferase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-03-20 — — US disclosed
US-7186701-B2 Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2007-03-06 — — US disclosed
US-20060240531-A1 Processes for producing isomaltose and isomaltitol and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-10-26 — — US disclosed
US-20060008791-A1 Dehydrating agent and method for dehydrating moist article using the agent and dehydrated article obtained by the method KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-01-12 — — US disclosed
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2005-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009017-A1 Alpha-isomaltosyltransferase, process for producing the same and use thereof UGGT1, B4GALT1, GALE KDM4E 2510/4885MAPT 985/4885KMT2A 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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