Dl-Tryptophan

Dl-Tryptophan

SCHEMBL4400705

CCC(C)C(N)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.76
▸ MAPT P10636 3/20 0.76
▸ KMT2A Q03164 3/20 0.76
▸ LMNA P02545 2/20 0.76
▸ TSHR P16473 2/20 0.76
▸ BLM P54132 2/20 0.76
▸ PMP22 Q01453 2/20 0.76
▸ MEN1 O00255 2/20 0.76
▸ MPO P05164 1/20 0.76
▸ HIF1A Q16665 1/20 0.76
▸ APAF1 O14727 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ RECQL P46063 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ HTR2A P28223 3/20 0.56
▸ HTR1A P08908 2/20 0.56
▸ HTR2C P28335 2/20 0.56
▸ SLC6A4 P31645 2/20 0.56
▸ HTR7 P34969 2/20 0.56
▸ HTR2B P41595 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL2060360 1.00 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL20504023 0.97 KDM4E (0.71) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL3857030 0.96 KDM4E (0.70) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL29183929 0.94 KDM4E (0.68) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL18249969 0.94 KDM4E (0.68) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28202459 0.93 KDM4E (0.65) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL22635845 0.92 KDM4E (0.64) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL5315679 0.91 KDM4E (0.63) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL7267888 0.91 KDM4E (0.63) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL9617704 0.91 KDM4E (0.63) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105134-A1 C-Terminally Pegylated Growth Hormones NOVO NORDISK A/S (DK) 2009-04-23 — — US claimed
US-20030104389-A1 Synthesis of biologically active compounds in cells SERGEEV PAVEL (CH) 2003-06-05 — — US claimed
EP-1208219-A1 SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS IN CELLS Sergeev, Pavel (CH) 2002-05-29 — — EP claimed
WO-2000061775-A1 SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS IN CELLS SERGEEV PAVEL (CH) 2000-10-19 — — WO claimed
CN-111386050-B Morbidity risk assessment device, morbidity risk assessment method, and computer-readable medium 国立大学法人九州大学 2024-02-06 — — CN disclosed
CN-116536191-A L-theanine faecal bacteria liquid and preparation method and application thereof 湖南农业大学 2023-08-04 — — CN disclosed
CN-113397056-A Feed for improving lean meat percentage of piglets and preparation method and application thereof 长春禾丰饲料有限责任公司 2021-09-17 — — CN disclosed
CN-111386050-A Disease risk evaluation device, disease risk evaluation method, program, and dementia prevention food 国立大学法人九州大学 2020-07-07 — — CN disclosed
US-20190145962-A1 PEPTIDE FOR INHIBITING BINDING OF AMYLOSPHEROIDS (ASPD), AND EVALUATION AND SCREENING METHOD TAO HEALTH LIFE PHARMA CO., LTD. (JP) 2019-05-16 — — US disclosed
CN-109706133-A One group of novel esterases and its application 上海交通大学 2019-05-03 — — CN disclosed
US-8795734-B2 Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-08-05 — — US disclosed
US-20130034610-A1 HYDROPHOBIC NANOTUBES AND NANOPARTICLES AS TRANSPORTERS FOR THE DELIVERY OF DRUGS INTO CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-02-07 — — US disclosed
US-8246995-B2 Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-08-21 — — US disclosed
US-7459443-B2 Oligonucleotide sequences for use as viricide or antitumor agents; biosynthesis SERGEEV PAVEL 2008-12-02 — — US disclosed
US-20060275371-A1 Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells UNIVERSITY, STANFORD 2006-12-07 — — US disclosed
US-20050026143-A1 Synthesis of biologically active compounds in cells SERGEEV PAVEL (CH) 2005-02-03 — — US disclosed
US-6831071-B2 Oligonucleotide sequences for use as viricide or antitumor agents SERGEEV PAVEL (CH) 2004-12-14 — — US disclosed
WO-2004080920-A1 HYDROPONIC PLANT NUTRIENT KIT AND METHOD OF USE ADVANCED NUTRIENTS LTD. (CA) 2004-09-23 — — WO disclosed
US-20030104389-A1 Synthesis of biologically active compounds in cells SERGEEV PAVEL (CH) 2003-06-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105134-A1 C-Terminally Pegylated Growth Hormones GHRHR, GHITM, HDGF KDM4E 4141/4885MAPT 3647/4885KMT2A 3669/4885
US-20050026143-A1 Synthesis of biologically active compounds in cells FBL, RNGTT, NOP2 KDM4E 4491/4885MAPT 4003/4885KMT2A 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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