SCHEMBL3857070

SCHEMBL3857070

CCN(C(N)=S)c1nc(C)cs1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
NOS1 P29475 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 4/20 0.35
LMNA P02545 3/20 0.35
NPC1 O15118 2/20 0.35
MAPT P10636 2/20 0.35
RAB9A P51151 2/20 0.35
CFTR P13569 2/20 0.34
GRM1 Q13255 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.30
SLC12A5 Q9H2X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27379137 0.78 NOS1 (0.31) NOS1SMN1; SMN2
SCHEMBL3647095 0.78 KDM4E (0.42) KDM4EALDH1A1LMNANPC1MAPT
SCHEMBL685578 0.74 SMN1; SMN2 (0.43) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA
SCHEMBL27528765 0.71 KDM4E (0.41) KDM4ENOS1SMN1; SMN2ALDH1A1MAPT
SCHEMBL4696485 0.71 GSTO1 (0.41) KDM4EALDH1A1LMNANPC1MAPT
SCHEMBL232983 0.71 SMN1; SMN2 (0.40) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA
SCHEMBL18674644 0.69 SLC29A1 (0.42) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA
SCHEMBL13634190 0.67 KDM4E (0.38) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA
SCHEMBL19724687 0.67 KMT2A (0.40) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA
SCHEMBL18674646 0.66 ALDH1A1 (0.39) KDM4ENOS1SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1818719-B1 Silver halide photographic material and image-forming method using the same FUJIFILM CORP (JP) 2013-01-16 EP disclosed
US-7592133-B2 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2009-09-22 US disclosed
US-20080268385-A1 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
EP-1818719-A1 Silver halide photographic material and image-forming method using the same FUJIFILM Corporation (JP) 2007-08-15 EP disclosed