Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859521 | 1.00 | PDCD1 (0.59) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL11673570 | 0.83 | FFAR1 (0.49) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL12434742 | 0.81 | FFAR1 (0.45) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL3787422 | 0.81 | DPP4 (0.62) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL812762 | 0.80 | PDCD1 (0.57) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL6346721 | 0.80 | FFAR1 (0.53) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL26545737 | 0.80 | FFAR1 (0.47) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL2922149 | 0.80 | RAB9A (0.52) | PDCD1CD274HTR7PDK2CNR2 | |
| SCHEMBL9890647 | 0.80 | PTGER1 (0.57) | PDCD1CD274FFAR1FFAR4HTR7 | |
| SCHEMBL28414965 | 0.80 | ACHE (0.55) | PDK2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |
| US-8440702-B2 | 1,3-oxazolidin -2-one derivatives useful as CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-05-14 | — | — | US | disclosed |
| US-20110178059-A1 | 1,3-OXAZOLIDIN -2-ONE DERIVATIVES USEFUL AS CETP INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-21 | — | — | US | disclosed |
| US-7915271-B2 | 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-03-29 | — | — | US | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-20090137548-A1 | 1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors | MERCK SHARP & DOHME LLC | 2009-05-28 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178059-A1 | 1,3-OXAZOLIDIN -2-ONE DERIVATIVES USEFUL AS CETP INHIBITORS | CETP, MTTP, APOB | PDCD1 2478/4885CD274 4162/4885FFAR1 1223/4885 |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | ALDH7A1, ADH5, ALDH1A1 | PDCD1 2615/4885CD274 1885/4885FFAR1 1269/4885 |
| US-20090137548-A1 | 1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors | CETP, MTTP, APOB | PDCD1 2478/4885CD274 4162/4885FFAR1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.