Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022649 | 0.89 | ESR2 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21116203 | 0.86 | USP8 (0.42) | CYP11B1CYP11B2GABRA1GABRG2GABRB3 | |
| SCHEMBL21479818 | 0.82 | CYP11B1 (0.42) | CYP11B1CYP11B2GABRG2GABRB3GABRA5 | |
| SCHEMBL2650416 | 0.82 | ESR2 (0.48) | CYP11B1CYP11B2GABRA1GABRG2GABRB3 | |
| SCHEMBL2651557 | 0.81 | BCAT1 (0.37) | CYP11B1CYP11B2GABRA1GABRG2GABRB3 | |
| SCHEMBL9069185 | 0.80 | ESR2 (0.47) | CYP11B1CYP11B2GABRA1GABRG2GABRB3 | |
| SCHEMBL4780146 | 0.79 | ADORA1 (0.46) | ADORA2AADORA1 | |
| SCHEMBL2573945 | 0.78 | CHKA (0.42) | CYP11B1CYP11B2CHUK | |
| SCHEMBL20989248 | 0.78 | NFE2L2 (0.48) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL2650000 | 0.77 | GABRA1 (0.42) | CYP11B1CYP11B2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585871-B2 | 4-{[(6R)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 3-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 4-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; cytokine expression | WYETH (US) | 2009-09-08 | — | — | US | disclosed |
| US-20060058337-A1 | Phenanthridine carbonyl phenols | WYETH (US) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058337-A1 | Phenanthridine carbonyl phenols | MT-CO2, PAH, CBR3 | CYP11B1 633/4885CYP11B2 413/4885GABRA1 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.