Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865100 | 1.00 | ITGB3 (0.64) | ITGB3ITGA2BACEITGAVPTPN1 | |
| SCHEMBL9636970 | 0.89 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL11747900 | 0.89 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL9157537 | 0.89 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL14343235 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BACEITGAVPTPN1 | |
| SCHEMBL16909032 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BACEITGAVPTPN1 | |
| SCHEMBL1087185 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BACEITGAVPTPN1 | |
| SCHEMBL3864558 | 0.87 | ITGB3 (0.50) | ITGB3ITGA2BCTSLCTSBCTSS | |
| SCHEMBL630884 | 0.86 | ITGB3 (0.69) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL630885 | 0.86 | ITGB3 (0.69) | ITGB3ITGA2BITGAVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521469-B2 | Phosphinic amino acid compounds | LES LABORATOIRES SERVIER (FR) | 2009-04-21 | — | — | US | disclosed |
| US-20080153890-A1 | Phosphinic Amino Acid Compounds | LES LABORATOIRES SERVER (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153890-A1 | Phosphinic Amino Acid Compounds | NPR1, NPPA, AADAT | ITGB3 3973/4885ITGA2B 4471/4885ACE 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.