Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652527 | 0.87 | MAP4K4 (0.55) | HDAC1HDAC2HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1927120 | 0.86 | L3MBTL1 (0.67) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL16248437 | 0.85 | LMNA (0.70) | HDAC1HDAC2HDAC8EPHX2HPGD | |
| SCHEMBL1925893 | 0.83 | SMN1; SMN2 (0.77) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL12757516 | 0.83 | HDAC8 (0.60) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL11675554 | 0.83 | PPARG (0.62) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL18759318 | 0.83 | CFD (0.61) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL4439622 | 0.82 | HDAC8 (0.64) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL1927498 | 0.82 | SMN1; SMN2 (0.76) | HDAC1HDAC2HDAC8EPHX2NR1H4 | |
| SCHEMBL5663566 | 0.82 | SMN1; SMN2 (0.58) | HDAC2EPHX2NR1H4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029148-A | N-phenyl-3- (2, 5-dioxopyrrolidin-1-yl) propionamide derivatives and similar compounds as DUX4 inhibitors for the treatment of, for example, neuromuscular diseases | 阿勒泰治疗公司 | 2026-05-12 | — | — | CN | disclosed |