Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717417 | 0.88 | ITGB3 (0.65) | PPARGHDAC1HDAC8HDAC2SMN1; SMN2 | |
| Betamipron SCHEMBL605899 | 0.84 | PRSS1 (0.70) | HDAC1HDAC8HDAC2EPHX2HPGD | |
| Betamipron SCHEMBL4498475 | 0.84 | PRSS1 (0.70) | HDAC1HDAC8HDAC2EPHX2HPGD | |
| SCHEMBL18759318 | 0.84 | CFD (0.61) | PPARGPPARAHDAC1HDAC8HDAC2 | |
| SCHEMBL12757516 | 0.84 | HDAC8 (0.60) | PPARGPPARAHDAC1HDAC8HDAC2 | |
| SCHEMBL1927120 | 0.84 | L3MBTL1 (0.67) | HDAC1HDAC8HDAC2NR1H4EPHX2 | |
| SCHEMBL26568779 | 0.83 | HPGD (0.74) | HDAC1HDAC8HDAC2NR1H4EPHX2 | |
| SCHEMBL38652196 | 0.83 | HDAC1 (0.59) | PPARGPPARAHDAC1HDAC8HDAC2 | |
| SCHEMBL3197946 | 0.82 | KDM4E (0.59) | HDAC1HDAC8HDAC2HPGDKDM4E | |
| SCHEMBL1925893 | 0.81 | SMN1; SMN2 (0.77) | PPARGPPARAHDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016287-A | COSMETIC AND ANTIINFLAMMATORY | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | disclosed |