Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175952 | 0.74 | PDE2A (0.76) | PDE2APARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL18362085 | 0.74 | PDE2A (0.43) | PDE2APARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL20156665 | 0.73 | HCAR2 (0.43) | HCAR2PARP1ALDH1A1ADORA3TNKS2 | |
| SCHEMBL6885305 | 0.70 | ALDH1A1 (0.42) | HCAR2KDM4EALDH1A1POLB | |
| SCHEMBL18362084 | 0.70 | PDE2A (1.00) | PDE2A | |
| SCHEMBL4128983 | 0.69 | PDE2A (0.40) | PDE2APARP1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL27409257 | 0.69 | KDM3B (0.41) | PARP1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15859525 | 0.65 | HCAR2 (0.55) | HCAR2ALDH1A1POLB | |
| SCHEMBL829306 | 0.64 | CYP2D6 (0.43) | HCAR2CYP2D6ALDH1A1 | |
| SCHEMBL8919174 | 0.64 | PIN1 (0.53) | HCAR2KDM4ECYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132132-A1 | 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2026-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132132-A1 | 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS | F11, F13B, F7 | PDE2A 1184/4885HCAR2 1194/4885PARP1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.