SCHEMBL38664459

SCHEMBL38664459

CC(C)(C)ONN(C(=O)NN)S(=O)(=O)c1cccc(F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 1/20 0.39
ABCC9 O60706 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
KCNJ8 Q15842 1/20 0.38
HSD11B1 P28845 1/20 0.38
PGR P06401 1/20 0.38
ATM Q13315 1/20 0.37
PTGER2 P43116 2/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
KMT2A Q03164 2/20 0.36
KAT6A Q92794 2/20 0.34
KCNJ6 P48051 1/20 0.34
KCNJ5 P48544 1/20 0.34
KCNJ3 P48549 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663831 0.88 GBA1 (0.32)
SCHEMBL38665833 0.87 HCRTR2 (0.40) HCRTR2ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL38666403 0.85 PGR (0.46) ABCC9ABCC8KCNJ11KCNJ8PGR
SCHEMBL38664976 0.84 SOS1 (0.38) HSD11B1KMT2ALMNAMEN1
SCHEMBL38665319 0.82 HSD11B1 (0.39) HSD11B1KMT2AMEN1
SCHEMBL38663087 0.79 PTGES (0.44) HCRTR2LMNAPOLB
SCHEMBL38665821 0.79 POLB (0.42) HCRTR2KMT2ALMNASMN1; SMN2MEN1
SCHEMBL38666046 0.78 TRPV4 (0.36) ABCC9ABCC8KCNJ11KCNJ8HSD11B1
SCHEMBL38665422 0.78 PTGES (0.46) PGRLMNA
SCHEMBL38663856 0.77 BMP1 (0.34) HCRTR2ABCC9ABCC8KCNJ11KCNJ8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed