Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953589 | 0.98 | NPC1 (0.74) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL296337 | 0.96 | NPC1 (0.84) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL9680520 | 0.92 | NPC1 (0.91) | NPC1RAB9AHTR7L3MBTL1LMNA | |
| SCHEMBL1040636 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL9680984 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL3424496 | 0.90 | NPC1 (0.87) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL315309 | 0.88 | RAB9A (0.69) | NPC1RAB9AHTR7L3MBTL1LMNA | |
| SCHEMBL28197598 | 0.84 | NPC1 (0.84) | NPC1RAB9AHTR7HDAC3HDAC4 | |
| SCHEMBL7417034 | 0.84 | NPC1 (0.77) | NPC1RAB9AHTR7L3MBTL1LMNA | |
| SCHEMBL15075713 | 0.84 | NPC1 (0.77) | NPC1RAB9AHTR7L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635782-B2 | Using microorganism in culture media; polylactones; biodegradable, melt processability | CANON KABUSHIKI KAISHA (JP) | 2003-10-21 | — | — | US | claimed |
| US-20020160467-A1 | Polyhydroxyalkanoate and manufacturing method thereof | CANON KABUSHIKI KAISHA (JP) | 2002-10-31 | — | — | US | claimed |
| EP-1188782-A2 | Polyhydroxyalkanoate and manufacturing method thereof | CANON KABUSHIKI KAISHA (JP) | 2002-03-20 | — | — | EP | claimed |
| EP-1255166-B1 | Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner | CANON KK (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-1255166-B1 | Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner | CANON KK (JP) | 2009-12-16 | — | — | EP | disclosed |
| US-7615233-B2 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2009-11-10 | — | — | US | disclosed |
| US-7615233-B2 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2009-11-10 | — | — | US | disclosed |
| US-7615233-B2 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2009-11-10 | — | — | US | disclosed |
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7527963-B2 | Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same | CANON KABUSHIKI KAISHA (JP) | 2009-05-05 | — | — | US | disclosed |
| US-20030194443-A1 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2003-10-16 | — | — | US | disclosed |
| US-20030153556-A1 | Piperazine and homopiperazine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
| CN-1431041-A | Granular material comprising polyhydroxyalkanoate and method for producing the same | CANON KK (JP) | 2003-07-23 | — | — | CN | disclosed |
| US-20030072594-A1 | Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner | CANON KABUSHIKI KAISHA (JP) | 2003-04-17 | — | — | US | disclosed |
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
| EP-1275378-A2 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | CANON KABUSHIKI KAISHA (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1255166-A2 | Binder resin containing novel polyhydroxyalkanoate, toner containing the binder resin, and image-forming method and image-forming apparatus which make use of the toner | CANON KABUSHIKI KAISHA (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-20020160467-A1 | Polyhydroxyalkanoate and manufacturing method thereof | CANON KABUSHIKI KAISHA (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1188782-A2 | Polyhydroxyalkanoate and manufacturing method thereof | CANON KABUSHIKI KAISHA (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194443-A1 | Particulate construct comprising polyhydroxyalkanoate and method for producing it | SQLE, FDFT1, CYP51A1 | NPC1 270/4885RAB9A 4597/4885HTR7 277/4885 |
| US-20030153556-A1 | Piperazine and homopiperazine compounds | HAMP, MPL, F2 | NPC1 3952/4885RAB9A 3654/4885HTR7 85/4885 |
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | NPC1L1, CYP46A1, NPC1 | NPC1 3/4885RAB9A 996/4885HTR7 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.