SCHEMBL3867797

SCHEMBL3867797

C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 13/20 1.00
ESR1 P03372 3/20 0.74
CYP3A4 P08684 2/20 0.74
ESR2 Q92731 2/20 0.74
ABCB11 O95342 2/20 0.74
SLC22A2 O15244 1/20 0.74
NR1I2 O75469 1/20 0.74
NR3C1 P04150 1/20 0.74
SHBG P04278 1/20 0.74
PGR P06401 1/20 0.74
HTR1A P08908 1/20 0.74
ADORA3 P0DMS8 1/20 0.74
AR P10275 1/20 0.74
ADRB3 P13945 1/20 0.74
CYP2B6 P20813 1/20 0.74
TBXA2R P21731 1/20 0.74
UGT1A1 P22309 1/20 0.74
SLC6A2 P23975 1/20 0.74
PDE4A P27815 1/20 0.74
ADORA2A P29274 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5324130 1.00 STS (1.00) STSESR1CYP3A4ESR2ABCB11
SCHEMBL19393201 1.00 STS (1.00) STSESR1CYP3A4ESR2ABCB11
SCHEMBL13266169 1.00 STS (1.00) STSESR1CYP3A4ESR2ABCB11
SCHEMBL5336088 0.90 STS (0.81) STSESR1CYP3A4ESR2ABCB11
SCHEMBL17775797 0.88 STS (0.79) STSESR1CYP3A4ESR2ABCB11
SCHEMBL14154435 0.88 STS (0.78) STSESR1CYP3A4ESR2ABCB11
SCHEMBL8937142 0.88 STS (0.78) STSESR1CYP3A4ESR2ABCB11
SCHEMBL27047081 0.87 STS (0.77) STSESR1CYP3A4ESR2ABCB11
SCHEMBL4903619 0.86 STS (1.00) STSESR1CYP3A4ESR2ABCB11
SCHEMBL4903623 0.86 STS (1.00) STSESR1CYP3A4ESR2ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583893-A1 COMPOSITIONS AND METHODS FOR IMPROVING OVARIAN FUNCTION Gameto, Inc. (US) 2025-07-16 EP disclosed
EP-3518933-B2 METHODS OF TREATING UTERINE FIBROIDS AND ENDOMETRIOSIS SUMITOMO PHARMA SWITZERLAND GMBH (CH) 2025-02-26 EP disclosed
US-11957684-B2 Treatment of heavy menstrual bleeding associated with uterine fibroids SUMITOMO PHARMA SWITZERLAND GMBH (CH) 2024-04-16 US disclosed
US-20240050625-A1 IMPLANT FOR OVARIAN DECLINE AND METHODS OF MANUFACTURING AN IMPLANT FOR OVARIAN DECLINE Gameto, Inc (US) 2024-02-15 US disclosed
WO-2024035964-A1 COMPOSITIONS AND METHODS FOR IMPROVING OVARIAN FUNCTION GAMETO, INC. (US) 2024-02-15 WO disclosed
CN-116284192-B Synthesis method of high-purity emamectin benzoate 南雄阳普医疗科技有限公司 2024-01-30 CN disclosed
US-11744920-B1 Implant for ovarian decline and methods of manufacturing an implant for ovarian decline Gameto, Inc (US) 2023-09-05 US disclosed
CN-116284192-A Synthesis method of high-purity emamectin benzoate 南雄阳普医疗科技有限公司 2023-06-23 CN disclosed
WO-2022165097-A9 METHODS OF ADMINISTRATING ELAGOLIX ABBVIE INC. (US) 2023-02-02 WO disclosed
EP-4094766-A1 METHODS OF TREATING UTERINE FIBROIDS AND ENDOMETRIOSIS Myovant Sciences GmbH (CH) 2022-11-30 EP disclosed
US-10788483-B2 Optimization method of a polynucleotide sequence VICTORIA LINK LIMITED (NZ) 2020-09-29 US disclosed
US-10758478-B2 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same LABORATORY SKIN CARE, INC. (US) 2020-09-01 US disclosed
US-20190255076-A1 SMALL MOLECULE THERAPEUTIC COMPOUNDS THAT REDUCE THE INCIDENCE OF INTRACEREBRAL HEMORRHAGE AND BRAIN MICROHEMMORHAGES ZEBRAPEUTICS INC. (CA) 2019-08-22 US disclosed
US-10023869-B2 Bio-sensor for the detection of small molecules Auramer Bio Limited (NZ) 2018-07-17 US disclosed
US-20170224823-A1 PLATINUM-CATALYZED SILICONE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF QUEEN'S UNIVERSITY BELFAST (GB) 2017-08-10 US disclosed
US-20170115281-A1 OPTIMISATION METHOD OF A POLYNUCLEOTIDE SEQUENCE VICTORIA LINK LIMITED (NZ) 2017-04-27 US disclosed
US-20110046599-A1 Multi-Day Delivery Of Biologically Active Substances SAMOS PHARMACEUTICALS LLC 2011-02-24 US disclosed
US-7538100-B2 17α-alkyl-17β-oxy-estratrienes and intermediate products for their production, use of the 17α-alkyl-17β-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-05-26 US disclosed
WO-2007113204-A2 METHOD FOR DETECTING AND CLASSIFYING ENDOCRINE DISRUPTOR COMPOUNDS VIB VZW (BE) 2007-10-11 WO disclosed
US-20060009436-A1 17alpha-alkyl-17beta-oxy-estratrienes and intermediate products for their production, use of the 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11957684-B2 Treatment of heavy menstrual bleeding associated with uterine fibroids GNRHR, SHBG, FSHR STS 3223/4885ESR1 17/4885CYP3A4 1281/4885
US-20060009436-A1 17alpha-alkyl-17beta-oxy-estratrienes and intermediate products for their production, use of the 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations CYP19A1, HSD17B11, CYP17A1 STS 80/4885ESR1 22/4885CYP3A4 105/4885
US-20110046599-A1 Multi-Day Delivery Of Biologically Active Substances GUSB, SERPINA6, CD44 STS 1776/4885ESR1 3448/4885CYP3A4 3497/4885
US-10758478-B2 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same CHERP, ORAI1, CA2 STS 4605/4885ESR1 2275/4885CYP3A4 4251/4885
US-20190255076-A1 SMALL MOLECULE THERAPEUTIC COMPOUNDS THAT REDUCE THE INCIDENCE OF INTRACEREBRAL HEMORRHAGE AND BRAIN MICROHEMMORHAGES DCX, FABP7, TFPI2 STS 4779/4885ESR1 4844/4885CYP3A4 4748/4885
US-20170224823-A1 PLATINUM-CATALYZED SILICONE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF CYP19A1, PGR, PGRMC2 STS 185/4885ESR1 47/4885CYP3A4 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.