Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 17/20 | 0.62 |
| ▸ | MME | P08473 | 15/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866600 | 1.00 | ECE1 (0.62) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL3865857 | 0.90 | ECE1 (0.68) | ECE1MMEACE2 | |
| SCHEMBL6923553 | 0.86 | ECE1 (0.68) | ECE1MMEACE2 | |
| SCHEMBL6929734 | 0.86 | ACE2 (0.73) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL6923179 | 0.85 | ECE1 (0.66) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL6928745 | 0.82 | ECE1 (0.77) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL3865859 | 0.82 | ECE1 (0.66) | ECE1MMEMMP8MMP14 | |
| SCHEMBL6928069 | 0.81 | ACE2 (0.81) | ECE1MMEACE2 | |
| SCHEMBL6924717 | 0.79 | ACE2 (0.84) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL9697199 | 0.78 | ACE2 (0.70) | ECE1MMEACE2MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521469-B2 | Phosphinic amino acid compounds | LES LABORATOIRES SERVIER (FR) | 2009-04-21 | — | — | US | disclosed |
| US-20080153890-A1 | Phosphinic Amino Acid Compounds | LES LABORATOIRES SERVER (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153890-A1 | Phosphinic Amino Acid Compounds | NPR1, NPPA, AADAT | ECE1 419/4885MME 1899/4885ACE2 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.