SCHEMBL3868593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2354757	0.89	KMT2A (0.58)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL3867743	0.82	KMT2A (0.59)	KMT2AALDH1A1LMNAKDM4EMEN1
	SCHEMBL2357637	0.81	CYP3A4 (0.61)	TNKSTNKS2KMT2AALDH1A1LMNA
	SCHEMBL3868598	0.78	ALDH1A1 (0.46)	TNKSTNKS2KMT2AALDH1A1LMNA
	SCHEMBL12024152	0.77	HTT (0.58)	KMT2AALDH1A1LMNAMEN1HPGD
	SCHEMBL24533635	0.77	CYP3A4 (0.60)	TNKSTNKS2KMT2AALDH1A1LMNA
	SCHEMBL18568687	0.75	CYP3A4 (0.54)	TNKSTNKS2KMT2AALDH1A1LMNA
	SCHEMBL24533663	0.73	USP2 (0.60)	KMT2AALDH1A1POLBRXFP1TP53
	SCHEMBL24533634	0.72	TSHR (0.81)	KMT2AALDH1A1LMNAMEN1POLB
	SCHEMBL12549629	0.72	TNKS (1.00)	TNKSTNKS2KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.