Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367556 | 0.80 | MEN1 (0.35) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL16519973 | 0.78 | TDP1 (0.48) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL15225588 | 0.76 | CA2 (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL17500355 | 0.73 | POLB (0.33) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL11502537 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL8723686 | 0.71 | CALM1 (0.44) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL5154337 | 0.71 | KMT2A (0.41) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL4690724 | 0.71 | TDP1 (0.41) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL3211253 | 0.71 | NPC1 (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL27676532 | 0.71 | GPR35 (0.51) | KMT2AMEN1MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601848-B2 | Multifunctional reagent for the synthesis of thiol modified oligomers | FIDICULA GMBH (DE) | 2009-10-13 | — | — | US | claimed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |