SCHEMBL7609159

SCHEMBL7609159

O=C(OCC1CC2CCC1C2)C1CC2C=CC1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 1/20 0.40
POLB P06746 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
HSD17B10 Q99714 2/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
ESR2 Q92731 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 2/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1088620 0.84 ALDH1A1 (0.39) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL417020 0.81 ALDH1A1 (0.46) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL19708550 0.81 ALDH1A1 (0.46) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL13197281 0.80 LMNA (0.46) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL22263738 0.79 ALDH1A1 (0.39) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL24255312 0.78 ALDH1A1 (0.46) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL1088893 0.77 ALDH1A1 (0.44) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL12481918 0.77 KDM4E (0.42) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL11907466 0.77 ALDH1A1 (0.45) ALDH1A1KMT2ARAB9APOLBTDP1
SCHEMBL3870190 0.76 ATM (0.43) ALDH1A1KMT2ARAB9APOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002128831-A NEW NORBORNENE-BASED COMPOUND, POLYMER OF THE SAME AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP 2002-05-09 JP disclosed