Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.55 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658623 | 0.90 | RELA (0.60) | RELAMGAMMEN1KMT2AMAPT | |
| SCHEMBL29585250 | 0.90 | SOST (0.53) | MGAMMEN1KMT2AMAPTHPGD | |
| SCHEMBL1699331 | 0.89 | HSD17B10 (0.52) | MGAMMEN1KMT2AMAPTHPGD | |
| SCHEMBL29365350 | 0.87 | CA12 (0.55) | RELAMGAMMEN1KMT2AMAPT | |
| SCHEMBL1279584 | 0.87 | SOST (0.60) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL1444961 | 0.87 | SOST (0.60) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL1279902 | 0.86 | SOST (0.59) | MGAMMEN1KMT2AMAPTHPGD | |
| SCHEMBL31290780 | 0.84 | XDH (0.53) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL30637413 | 0.82 | RELA (0.58) | RELAMGAMMEN1KMT2AMAPT | |
| SCHEMBL31621907 | 0.80 | KMT2A (0.50) | MGAMMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143318-A1 | DEGRANULATION INHIBITOR | TROPICAL TECHNOLOGY CENTER LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-2025680-A1 | DEGRANULATION INHIBITOR | Tropical Technology Center Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143318-A1 | DEGRANULATION INHIBITOR | CMA1, MRGPRX1, MRGPRX2 | RELA 337/4885MGAM 157/4885MEN1 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.