Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279584 | 0.99 | SOST (0.60) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL1444961 | 0.99 | SOST (0.60) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL1699331 | 0.90 | HSD17B10 (0.52) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL29585250 | 0.89 | SOST (0.53) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL3870280 | 0.86 | RELA (0.56) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL1279487 | 0.84 | MAPT (0.54) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL31290780 | 0.83 | XDH (0.53) | SOSTMEN1KMT2AMAPTHPGD | |
| Ellagic Acid SCHEMBL1279897 | 0.83 | KDM4E (0.62) | SOSTMEN1KMT2AMAPTHPGD | |
| Ellagic Acid SCHEMBL1279583 | 0.82 | KDM4E (0.60) | SOSTMEN1KMT2AMAPTHPGD | |
| SCHEMBL1279510 | 0.80 | MAPT (0.54) | SOSTMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351492-B2 | Anti-biofilm compositions and methods for using | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-05-31 | — | — | US | claimed |
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2014-09-18 | — | — | US | claimed |
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | claimed |
| EP-2624702-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | The Board of Trustees of The University of Arkansas (US) | 2013-08-14 | — | — | EP | claimed |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | US | claimed |
| WO-2012048119-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | WO | claimed |
| US-9351492-B2 | Anti-biofilm compositions and methods for using | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2624702-B1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | UNIV ARKANSAS (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2014-09-18 | — | — | US | disclosed |
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | disclosed |
| EP-2624702-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | The Board of Trustees of The University of Arkansas (US) | 2013-08-14 | — | — | EP | disclosed |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | US | disclosed |
| WO-2012048119-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | SOST 546/4885MEN1 4822/4885KMT2A 2809/4885 |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | SOST 546/4885MEN1 4822/4885KMT2A 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.