Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870310 | 1.00 | KDM4E (0.70) | KDM4ETSHRRECQLHSD17B10MAPK1 | |
| SCHEMBL3871074 | 1.00 | KDM4E (0.70) | KDM4ETSHRRECQLHSD17B10MAPK1 | |
| SCHEMBL1797273 | 0.79 | SERPINE1 (0.51) | KDM4ETSHRRECQLHSD17B10MAPK1 | |
| SCHEMBL1800176 | 0.79 | SERPINE1 (0.51) | KDM4ETSHRRECQLHSD17B10MAPK1 | |
| SCHEMBL1797272 | 0.79 | SERPINE1 (0.51) | KDM4ETSHRRECQLHSD17B10MAPK1 | |
| SCHEMBL539118 | 0.77 | EP300 (0.49) | KDM4ETSHRHSD17B10CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL418780 | 0.76 | ROCK2 (0.47) | KDM4ETSHRRECQLHSD17B10NPSR1 | |
| Hydrochloric Acid SCHEMBL418781 | 0.76 | ROCK2 (0.47) | KDM4ETSHRRECQLHSD17B10NPSR1 | |
| SCHEMBL495339 | 0.76 | YAP1 (0.65) | KDM4ERAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL539174 | 0.75 | KDM4E (0.51) | KDM4ETSHRHSD17B10KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | KDM4E 4309/4885TSHR 2186/4885RECQL 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.