Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214460 | 0.88 | BCAT2 (0.63) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL27704997 | 0.84 | BCAT2 (0.59) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL623796 | 0.84 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL4151580 | 0.81 | BCAT2 (0.59) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL407835 | 0.81 | BCAT2 (0.55) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL2025737 | 0.81 | BCAT2 (0.71) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL530286 | 0.81 | FABP4 (0.57) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL29712321 | 0.81 | BCAT2 (0.55) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL16914158 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDMAPTTSHR | |
| Propionamide SCHEMBL28350452 | 0.80 | HNF4A (0.47) | KDM4EALDH1A1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915337-A4 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2009-04-22 | — | — | EP | claimed |
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | AMOREPACIFIC CORPORATION (KR) | 2008-11-13 | — | — | US | claimed |
| CN-101243042-A | Hydroxybenzamide derivatives, the method for preparing thereof and the cosmetic composition containing the same | AMOREPACIFIC CORP (KR) | 2008-08-13 | — | — | CN | claimed |
| EP-1915337-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | Amorepacific Corporation (KR) | 2008-04-30 | — | — | EP | claimed |
| WO-2007021067-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-02-22 | — | — | WO | claimed |
| EP-1915337-A4 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2009-04-22 | — | — | EP | disclosed |
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | AMOREPACIFIC CORPORATION (KR) | 2008-11-13 | — | — | US | disclosed |
| CN-101243042-A | Hydroxybenzamide derivatives, the method for preparing thereof and the cosmetic composition containing the same | AMOREPACIFIC CORP (KR) | 2008-08-13 | — | — | CN | disclosed |
| EP-1915337-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | Amorepacific Corporation (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007021067-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-02-22 | — | — | WO | disclosed |
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | H1-0, HAAO, H1-10 | KDM4E 621/4885ALDH1A1 96/4885HPGD 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.