Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.61 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289270 | 0.81 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL3347086 | 0.81 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL3816367 | 0.81 | KMT2A (0.59) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL11816880 | 0.80 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL8900626 | 0.80 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL6964088 | 0.78 | SMN1; SMN2 (0.64) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL1921316 | 0.77 | ALDH1A1 (0.67) | RAB9ANPC1SMN1; SMN2PKMHPGD | |
| SCHEMBL15988688 | 0.76 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2PKMCDK5 | |
| SCHEMBL8708792 | 0.76 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2PAX8HPGD | |
| SCHEMBL5788885 | 0.75 | CES2 (0.67) | RAB9ANPC1SMN1; SMN2PKMCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473695-B2 | 4-imidazolin-2-one compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-06 | — | — | US | disclosed |