Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3162890 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7266631 | 0.79 | KMT2A (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3816367 | 0.77 | KMT2A (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1921316 | 0.77 | ALDH1A1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3870748 | 0.76 | RAB9A (0.61) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7362770 | 0.76 | CES2 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL9669231 | 0.72 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AKDM4ECES2 | |
| SCHEMBL15618059 | 0.72 | TDP1 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL5162864 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL397225 | 0.71 | CES2 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788360-A4 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT INC (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0788360-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | PROSCRIPT, INC. (US) | 1997-08-13 | — | — | EP | claimed |
| CN-1051299-C | Tetrahydrophthamide derivative medium for preparation of same, preparation of same and herbcide which uses same as effective composition | SAGAMI CHEM RES (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1084847-A | Tetrahydrochysene butyl benzene orthobenzol diacid amide derivative and its preparation intermediate and manufacture method thereof and with its weedicide as effective constituent | SAGAMI CHEM RES (JP) | 1994-04-06 | — | — | CN | disclosed |