Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090333 | 0.97 | KMT2A (0.45) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL31277089 | 0.92 | KMT2A (0.40) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL6978161 | 0.87 | — | — | |
| SCHEMBL7085369 | 0.87 | EPHX1 (0.54) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| Cyclohexane SCHEMBL3394348 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL6946772 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL5711897 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL175425 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL14679380 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 | |
| SCHEMBL11098596 | 0.79 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550277-B2 | D-amino acid dehydrogenase and method of making D-amino acids | CODEXIS, INC. (US) | 2009-06-23 | — | — | US | claimed |
| US-20080182972-A1 | D-amino acid dehydrogenase and method of making D-amino acids | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2008-07-31 | — | — | US | claimed |
| EP-1896574-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BioCatalytics Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006113085-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BIOCATALYTICS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-5854035-A | Enzyme with leuDH activity, nucleotide sequence coding therefor and process for the prepartion of the enzyme | DEGUSSA AG (DE) | 1998-12-29 | — | — | US | claimed |
| EP-0792933-A2 | Enzyme having LeuDH activity, nucleotide sequence coding therefor and process for the preparation of this enzyme | Degussa Aktiengesellschaft (DE) | 1997-09-03 | — | — | EP | claimed |
| CN-110003235-B | Isoxazole succinimide compound and synthetic method thereof | 上海大学 | 2022-01-07 | — | — | CN | disclosed |
| US-20160319312-A1 | SYNTHESIS METHOD FOR L-CYCLIC ALKYL AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF | TIANJIN ASYMCHEM PHARMACEUTICAL CO., LTD. (CN) | 2016-11-03 | — | — | US | disclosed |
| US-20160319312-A1 | SYNTHESIS METHOD FOR L-CYCLIC ALKYL AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF | TIANJIN ASYMCHEM PHARMACEUTICAL CO., LTD. (CN) | 2016-11-03 | — | — | US | disclosed |
| US-7550277-B2 | D-amino acid dehydrogenase and method of making D-amino acids | CODEXIS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2008-08-07 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188448-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, PGRMC2 | EPHX1 1519/4885HPGD 79/4885KMT2A 1671/4885 |
| US-20160319312-A1 | SYNTHESIS METHOD FOR L-CYCLIC ALKYL AMINO ACID AND PHARMACEUTICAL COMPOSITION HAVING THEREOF | ADH1B, BCAT2, BCAT1 | EPHX1 2486/4885HPGD 92/4885KMT2A 730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.