Acetic Acid

Acetic Acid

SCHEMBL3872537

C=CCn1cc[n+](CC=C)c1.CC(=O)[O-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSP90AA1 P07900 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FDPS P14324 4/20 0.32
POLB P06746 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL15118275 0.94 ALDH1A1 (0.35) ALDH1A1GAAMEN1KMT2AHSP90AA1
Bicarbonate SCHEMBL15118277 0.92 ALDH1A1 (0.34) ALDH1A1GAAMEN1KMT2AHSP90AA1
SCHEMBL87311 0.87 ALDH1A1 (0.30) ALDH1A1GAA
SCHEMBL19857303 0.85
Water SCHEMBL15361762 0.85
Hydrochloric Acid SCHEMBL572630 0.85
Bromide SCHEMBL1045353 0.85 ALDH1A1 (0.33) ALDH1A1GAA
Iodide SCHEMBL2341576 0.85 ALDH1A1 (0.33) ALDH1A1GAA
Bromide SCHEMBL30218911 0.85
SCHEMBL1487865 0.84 KDM4E (0.31) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2108065-B1 METHOD FOR THE PRODUCTION OF MOLDED BODIES FROM PROTEINS HAVING IONIC LIQUIDS THUERINGISCHES INST TEXTIL (DE) 2012-12-05 EP claimed
CN-101400836-A Method for the production of molded bodies from proteins having ionic liquids THUERINGISCHES INST TEXTIL (DE) 2009-04-01 CN claimed
US-20090051068-A1 Method for Producing Molded Bodies from Proteins THÜRINGISCHES INSTITUTE FÜR TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) 2009-02-26 US claimed
US-9162999-B2 Catalytic conversion of cellulose to fuels and chemicals using boronic acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-10-20 US disclosed
WO-2015131933-A1 METHOD OF PRODUCING GRAPHENE BY EXFOLIATION OF GRAPHITE Westfälische Wilhelms-Universität Münster (DE) 2015-09-11 WO disclosed
US-9085525-B2 Processes employing cyclodextrin derivative quaternary salts MATOS JOSE R (US) 2015-07-21 US disclosed
EP-2692413-B1 Ionic liquids for selective sulfur dioxide absorption CHEMIEFASER LENZING AG (AT) 2015-02-25 EP disclosed
US-20140046061-A1 Processes Employing Cyclodextrin Derivative Quaternary Salts MATOS JOSE R (US) 2014-02-13 US disclosed
WO-2014020071-A1 IONIC LIQUIDS FOR SELECTIVE SULFUR DIOXIDE ABSORPTION LENZING AKTIENGESELLSCHAFT (AT) 2014-02-06 WO disclosed
EP-2692413-A1 Ionic liquids for selective sulfur dioxide absorption LENZING AKTIENGESELLSCHAFT (AT) 2014-02-05 EP disclosed
US-8492538-B1 Cyclodextrin derivative salts MATOS JOSE R (US) 2013-07-23 US disclosed
US-20130178617-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2013-07-11 US disclosed
WO-2013049424-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-04 WO disclosed
CN-101400836-B Method for the production of molded bodies from proteins having ionic liquids and molded bodies therefor THUERINGISCHES INST TEXTIL 2012-06-13 CN disclosed
EP-2108065-A1 METHOD FOR THE PRODUCTION OF MOLDED BODIES FROM PROTEINS HAVING IONIC LIQUIDS THÜRINGISCHES INSTITUT FÜR TEXTIL- UND KUNSTSTOFF-FORSCHUNG E.V. (DE) 2009-10-14 EP disclosed
CN-101400836-A Method for the production of molded bodies from proteins having ionic liquids THUERINGISCHES INST TEXTIL (DE) 2009-04-01 CN disclosed
US-20090051068-A1 Method for Producing Molded Bodies from Proteins THÜRINGISCHES INSTITUTE FÜR TEXTIL-UND KUNSTSTOFF-FORSCHUNG E.V. (DE) 2009-02-26 US disclosed
WO-2008083707-A1 METHOD FOR THE PRODUCTION OF MOLDED BODIES FROM PROTEINS HAVING IONIC LIQUIDS Thüringisches Institut für Textil-und Kunststoff-Forschung E.V. (DE) 2008-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178617-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS MGAM, CA2, CA6 ALDH1A1 3895/4885GAA 636/4885MEN1 461/4885
US-20140046061-A1 Processes Employing Cyclodextrin Derivative Quaternary Salts PICALM, SI, PDCD2L ALDH1A1 4330/4885GAA 384/4885MEN1 3715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.