Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560987 | 0.80 | POLB (0.83) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL18624977 | 0.80 | POLB (0.83) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL150334 | 0.79 | LMNA (0.77) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL10590842 | 0.78 | POLB (0.59) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL3872941 | 0.78 | POLB (0.59) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL29990536 | 0.76 | LMNA (0.65) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL525918 | 0.76 | LMNA (0.65) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL3171676 | 0.76 | LMNA (0.65) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL447639 | 0.76 | LMNA (0.65) | POLBCYP2D6LMNAALDH1A1TSHR | |
| SCHEMBL1807437 | 0.76 | POLB (0.57) | POLBCYP2D6LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610298-A | Water-soluble anthraquinone compounds, preparation thereof and use thereof as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |