SCHEMBL1807437

SCHEMBL1807437

C[N]c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
CYP2D6 P10635 1/20 0.57
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.56
NT5E P21589 1/20 0.56
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.48
RPS6KA3 P51812 1/20 0.47
TDP1 Q9NUW8 2/20 0.45
PHLPP2 Q6ZVD8 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
KDM4E B2RXH2 2/20 0.38
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877158 0.82 POLB (0.64) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL15355805 0.82 POLB (0.64) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL13154694 0.80 POLB (0.68) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL18624977 0.80 POLB (0.83) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL28560987 0.80 POLB (0.83) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL150334 0.79 LMNA (0.77) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL3872941 0.78 POLB (0.59) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL10590842 0.78 POLB (0.59) POLBCYP2D6ALDH1A1TSHRNT5E
SCHEMBL7056902 0.78 ENPP2 (0.52) SMN1; SMN2CA12CA2CA9MAPT
SCHEMBL8761533 0.77 CYP2D6 (0.53) POLBCYP2D6ALDH1A1TSHRNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP claimed
US-4138558-A Anthraquinone compounds NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1979-02-06 US claimed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110216117-A1 WATER-SOLUBLE AZO COMPOUND OR SALT THEREOF, INK COMPOSITION, AND COLORED MATTER NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-09-08 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
EP-0962500-B1 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-01-28 EP disclosed
EP-0951515-B1 MULTICOLOUR INK JET PRINTING METHOD AVECIA LTD (GB) 2003-04-16 EP disclosed
US-6336721-B1 PRINTING FIRST AND SECOND SET OF INKS ONTO SUBSTRATE, WHEREIN FIRST SET COMPRISES ONE OR MORE INKS EACH CONTAINING COLORANT SELECTED FROM YELLOW, MAGENTA, CYAN AND BLACK, AND SECOND SET COMPRISES ONE OR MORE INKS EACH CONTAINING SPECIFIED DYE ZENECA LIMITED (GB) 2002-01-08 US disclosed
US-6114511-A FIBER REACTIVE MONOAZO DYES, ARE CAPABLE OF DYEING HYDROXYL-AND/OR CARBOXAMIDO-CONTAINING MATERIAL, ESPECIALLY FIBER MATERIAL SUCH AS COTTON, WOOL, SYNTHETIC POLYAMIDE OR POLYESTER FIBERS, HIGH COLOR STRENGTH AND FASTNESS DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2000-09-05 US disclosed
EP-0962500-A1 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs DyStar Textilfarben GmbH & Co., Textilfarben Deutschland KG (DE) 1999-12-08 EP disclosed
EP-0951515-A1 MULTICOLOUR INK JET PRINTING METHOD ZENECA LIMITED (GB) 1999-10-27 EP disclosed
WO-1998029513-A1 MULTICOLOUR INK JET PRINTING METHOD AVECIA LIMITED (GB) 1998-07-09 WO disclosed
US-5118826-A Colorfastness CIBA-GEIGY CORPORATION (US) 1992-06-02 US disclosed
EP-0260806-B1 COLORATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-08 EP disclosed
US-5021557-A Copper-containing formazan dye, colorfast blue shades on cellulose CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
US-4881942-A HEATING, FIXING, CONTROLLING PH TO 5.8 TO 8.0 IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-21 US disclosed
EP-0333656-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1989-09-20 EP disclosed
EP-0260806-A2 Coloration process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-23 EP disclosed
US-4693726-A Process for dyeing or printing cellulose fibers or cellulose blend fibers with pyridinium-triazine reactive dye, axable without alkali HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-15 US disclosed
EP-0202436-A2 Process for dyeing or printing cellulosic fibres or cellulosic mixed fibres HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 POLB 3927/4885CYP2D6 2352/4885ALDH1A1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.