Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.45 |
| ▸ | FEN1 | P39748 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410363 | 0.90 | MEN1 (0.47) | ALOX5APFEN1MEN1KMT2AUBE2M | |
| SCHEMBL3874676 | 0.83 | UBE2M (0.45) | ALOX5APFEN1MEN1KMT2AUBE2M | |
| SCHEMBL3885085 | 0.83 | ALOX5AP (0.49) | ALOX5APFEN1MEN1KMT2AUBE2M | |
| SCHEMBL3877890 | 0.80 | ALOX5AP (0.45) | ALOX5APFEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL3886420 | 0.79 | HPGDS (0.52) | ALOX5APFEN1MEN1KMT2APDE2A | |
| SCHEMBL3874494 | 0.79 | MEN1 (0.48) | ALOX5APFEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL3880121 | 0.78 | MEN1 (0.48) | ALOX5APFEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL3881888 | 0.75 | HSD11B1 (0.61) | MEN1KMT2AALDH1A1LMNAGRM5 | |
| SCHEMBL410528 | 0.74 | POLB (0.48) | ALOX5APFEN1MEN1KMT2AUBE2M | |
| SCHEMBL3875010 | 0.74 | ALOX5AP (0.45) | ALOX5APFEN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2030970-A1 | Allosteric modulators of metabotropic glutamate receptors | ADDEX Pharma S.A. (CH) | 2009-03-04 | — | — | EP | claimed |
| EP-1685105-B1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2008-10-15 | — | — | EP | claimed |