Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258015 | 0.82 | PDK2 (0.62) | PDK2 | |
| SCHEMBL6856357 | 0.82 | PDK2 (0.62) | PDK2 | |
| SCHEMBL991993 | 0.75 | KDM4E (0.41) | PDK2 | |
| SCHEMBL3741162 | 0.75 | KDM4E (0.41) | PDK2 | |
| SCHEMBL7707020 | 0.75 | KDM4E (0.41) | PDK2 | |
| SCHEMBL13308755 | 0.72 | PDK2 (0.62) | PDK2 | |
| SCHEMBL23295742 | 0.72 | ITGA4 (0.32) | PDK2 | |
| SCHEMBL134324 | 0.72 | HTR2A (0.38) | PDK2 | |
| SCHEMBL8816141 | 0.71 | PDK2 (0.48) | PDK2 | |
| SCHEMBL9616256 | 0.71 | PDK2 (0.50) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482490-B2 | Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound | TOSOH CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TOSOH CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1752440-A1 | AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND | Tosoh Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| EP-1400578-B1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | TOSOH CORP (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | PDK2 2093/4885 |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TAAR1, SLC18A1, ADRB2 | PDK2 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.