Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | CTSV | O60911 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | PPIA | P62937 | 2/20 | 0.35 |
| ▸ | PPIF | P30405 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947751 | 0.89 | MEN1 (0.42) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3874013 | 0.76 | HTR1A (0.44) | MEN1KMT2ANPC1RAB9ASGMS2 | |
| SCHEMBL27764455 | 0.76 | POLB (0.39) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3587958 | 0.74 | PPIA (0.41) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL4942752 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3581595 | 0.73 | POLB (0.47) | NPC1RAB9APOLB | |
| SCHEMBL1447240 | 0.72 | POLB (0.46) | NPC1RAB9APOLB | |
| SCHEMBL3590056 | 0.72 | EIF4E (0.44) | MEN1KMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3593506 | 0.71 | CTSV (0.42) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL3581708 | 0.71 | TUBB4A (0.41) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027091-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - Portela & Ca., S.A. (PT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007117165-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & CA, S.A. (PT) | 2007-10-18 | — | — | WO | disclosed |