Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.63 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873777 | 1.00 | IMPDH2 (0.63) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL382594 | 0.86 | GAA (0.58) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL29055513 | 0.81 | IMPDH2 (0.59) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL25782141 | 0.81 | KDM4E (0.50) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL3875962 | 0.81 | CDK4 (0.50) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL3886228 | 0.81 | IMPDH2 (0.59) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| Carbazole SCHEMBL27962774 | 0.79 | ALDH1A1 (0.70) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL3884410 | 0.79 | ESR1 (0.46) | IMPDH2IMPDH1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL22163286 | 0.78 | IMPDH2 (0.60) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 | |
| SCHEMBL31780731 | 0.78 | IMPDH2 (1.00) | IMPDH2IMPDH1CDK4CCND1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104562040-B | Azacyclo-modified polysiloxane corrosion inhibitor composition and preparation method thereof | 中国石油化工股份有限公司 | 2017-05-17 | — | — | CN | claimed |
| US-9289414-B2 | Carbazole formulations for the treatment of psoriasis and angiogenesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-22 | — | — | US | claimed |
| CN-104562040-A | Azacyclo-modified polysiloxane corrosion inhibitor composition and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| CN-117924369-A | Phosphite group-containing carbazole polymerization inhibitor, preparation method and application thereof | 万华化学集团股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20230309380-A1 | COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS | IDEMITSU KOSAN CO.,LTD. (JP) | 2023-09-28 | — | — | US | disclosed |
| CN-111286020-B | Preparation method of polyether polyol with fluorescent characteristic | 山东蓝星东大有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-111286020-A | Preparation method of polyether polyol with fluorescent characteristic | 山东蓝星东大有限公司 | 2020-06-16 | — | — | CN | disclosed |
| CN-104562040-B | Azacyclo-modified polysiloxane corrosion inhibitor composition and preparation method thereof | 中国石油化工股份有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-103764143-B | Lipoxygenase inhibitors | 斯坦福国际咨询研究所 | 2017-05-03 | — | — | CN | disclosed |
| CN-104562040-A | Azacyclo-modified polysiloxane corrosion inhibitor composition and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| US-7491245-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | disclosed |
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | IMPDH2 2923/4885IMPDH1 2771/4885CDK4 694/4885 |
| US-20230309380-A1 | COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS | PIEZO1, OR10J3, TMEM109 | IMPDH2 2892/4885IMPDH1 2297/4885CDK4 2237/4885 |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | IMPDH2 2923/4885IMPDH1 2771/4885CDK4 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.