SCHEMBL3875286

SCHEMBL3875286

Cc1cc(OCCN)ccc1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
PDIA6 Q15084 1/20 0.45
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LTA4H P09960 2/20 0.44
PLA2G2A P14555 1/20 0.44
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13177803 0.91 CARM1 (0.48) CARM1PDIA6NPC1MAPTHTT
SCHEMBL10702555 0.90 ALDH1A1 (0.50) CARM1PDIA6NPC1MAPTHTT
SCHEMBL10702177 0.88 PDIA6 (0.56) CARM1PDIA6NPC1MAPTHTT
SCHEMBL10870432 0.88 PDIA6 (0.51) CARM1PDIA6NPC1MAPTHTT
SCHEMBL10870020 0.86 PDIA6 (0.54) CARM1PDIA6NPC1MAPTHTT
SCHEMBL11650358 0.86 PDIA6 (0.54) CARM1PDIA6NPC1MAPTHTT
SCHEMBL26023458 0.85 NPC1 (0.48) CARM1PDIA6NPC1MAPTHTT
SCHEMBL11444520 0.85 SKP2 (0.55) PDIA6NPC1MAPTHTTRAB9A
SCHEMBL10187313 0.85 MAPT (0.53) PDIA6NPC1MAPTHTTRAB9A
SCHEMBL8091595 0.84 DRD2 (0.51) CARM1TAAR1PDIA6NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
US-7485155-B2 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color L'OREAL S.A. (FR) 2009-02-03 US claimed
US-20060156478-A1 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color L'OREAL S.A. (FR) 2006-07-20 US claimed
EP-1674075-A1 Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
EP-1674074-A1 Colored hair treating process with a composition comprising a specific non ionic and/or an amphoteric and/or a mild anionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
WO-2020140055-A1 CYCLIN-DEPENDENT KINASE INHIBITORS SPV THERAPEUTICS INC. (US) 2020-07-02 WO disclosed
WO-2020140052-A1 CYCLIN-DEPENDENT KINASE INHIBITORS SPV THERAPEUTICS INC. (US) 2020-07-02 WO disclosed
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP disclosed
US-7485155-B2 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color L'OREAL S.A. (FR) 2009-02-03 US disclosed
US-20060156478-A1 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color L'OREAL S.A. (FR) 2006-07-20 US disclosed
EP-1674075-A1 Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP disclosed
US-5932582-A Fibrinogen receptor antagonist prodrugs MERCK & CO., INC. (US) 1999-08-03 US disclosed
EP-0912513-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS Merck & Co., Inc. (US) 1999-05-06 EP disclosed
WO-1998000401-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS MERCK & CO., INC. (US) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060156478-A1 Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color KRT18, DSG1, DSP CARM1 2196/4885TAAR1 2358/4885PDIA6 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.