Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624254 | 0.85 | ALDH1A1 (0.53) | ALOX5GPR3MAPTALDH1A1RAB9A | |
| SCHEMBL30017926 | 0.85 | ALDH1A1 (0.53) | ALOX5GPR3MAPTALDH1A1RAB9A | |
| SCHEMBL22232939 | 0.82 | ALOX5 (0.53) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL20441891 | 0.81 | PTPN1 (0.47) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL3876656 | 0.81 | ALOX5 (0.51) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL30594903 | 0.81 | ALOX5 (0.51) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL3886328 | 0.81 | MAPT (0.47) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL19443961 | 0.81 | ALOX5 (0.51) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL15497424 | 0.80 | GPR3 (0.68) | ALOX5GPR3PARP14MAPTALDH1A1 | |
| SCHEMBL3885289 | 0.80 | ATP1A1 (0.38) | ALOX5PTPN22MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| EP-2816072-B1 | COMPOSITE POLYAMIDE PARTICLES AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-9416233-B2 | Composite polyamide fine particles and method of producing same | TORAY INDUSTRIES, INC. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150031834-A1 | COMPOSITE POLYAMIDE FINE PARTICLES AND METHOD OF PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2015-01-29 | — | — | US | disclosed |
| EP-2816072-A1 | COMPOSITE POLYAMIDE PARTICLES AND METHOD FOR PRODUCING SAME | Toray Industries, Inc. (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-7491245-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | disclosed |
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | ALOX5 1116/4885GPR3 4420/4885PARP14 2647/4885 |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | ALOX5 1116/4885GPR3 4420/4885PARP14 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.