SCHEMBL38788

SCHEMBL38788

C=CC(=O)NCCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.57
ZDHHC2 Q9UIJ5 1/20 0.57
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
PRMT1 Q99873 1/20 0.48
ADRA1A P35348 1/20 0.45
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TGM2 P21980 1/20 0.44
ABCC4 O15439 1/20 0.43
LMNA P02545 3/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35903 0.94 ZDHHC20 (0.60) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1015381 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL15463341 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1083120 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL16229524 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1018094 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1018444 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL707155 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1332462 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR
SCHEMBL1334526 0.92 ZDHHC20 (0.63) ZDHHC20ZDHHC2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705390-B9 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2025-01-22 EP claimed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 US claimed
CN-117270235-A Contact lens having a lubricious coating thereon 爱尔康公司 2023-12-22 CN claimed
EP-2705390-B2 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2023-11-15 EP claimed
CN-111566517-B Contact lens having a lubricious coating thereon 爱尔康公司 2023-11-10 CN claimed
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 CN claimed
EP-4017478-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS Alcon Inc. (CH) 2022-06-29 EP claimed
EP-3778039-B1 DIGITAL PRINTING INKS SUN CHEMICAL CORP (US) 2022-04-06 EP claimed
EP-3746820-B1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC (CH) 2022-02-16 EP claimed
US-11021620-B2 Digital printing inks SUN CHEMICAL CORPORATION (US) 2021-06-01 US claimed
US-20070102347-A1 Temperature-responsive membrane, temperature-responsive membrane module, and membrane filtration system in which the same are used KABUSHIKI KAISHA TOSHIBA 2007-05-10 US claimed
EP-1735082-A1 MATERIALS, METHODS, AND SYSTEMS FOR SEPARATING AND IDENTIFYING PROTEINS FROM MIXTURES Ciphergen Biosystems, Inc. (US) 2006-12-27 EP claimed
US-20050227001-A1 Materials, methods and systems for separating and identifying proteins from mixtures CIPHERGEN BIOSYSTEMS INC. 2005-10-13 US claimed
WO-2005089911-A1 MATERIALS, METHODS, AND SYSTEMS FOR SEPARATING AND IDENTIFYING PROTEINS FROM MIXTURES CIPHERGEN BIOSYSTEMS, INC. (US) 2005-09-29 WO claimed
WO-2005054548-A2 METHODS, COMPOSITIONS, AND KITS FOR PROTEIN CRYSTALLIZATION INVITROGEN CORPORATION (US) 2005-06-16 WO claimed
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA ACHILION PHARMACEUTICALS 2003-10-23 US claimed
WO-2003060098-A2 METHODS FOR IDENTIFYING COMPOUNDS WHICH INHIBIT BINDING OF NUCLEOCAPSID 7 PROTEIN TO HIV-1 RNA ACHILLION PHARMACEUTICALS, INC. (US) 2003-07-24 WO claimed
EP-0425590-B1 PROCESS FOR STABILISING THE pH OF AQUEOUS FEED SOLUTIONS AND FOR ABSORBING AND BUFFERING URINE AND WOUND SECRETIONS MARIGEN SA (CH) 1993-12-15 EP claimed
US-5173160-A ANALYSIS OF CARRIER AMPHOLYTES USING IMMOBILIZED PH GRADIENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-12-22 US claimed
WO-1992015870-A1 ANALYSIS OF CARRIER AMPHOLYTES USING IMMOBILIZED PH GRADIENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-09-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 ZDHHC20 2735/4885ZDHHC2 3795/4885ALDH1A1 1339/4885
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA MRPS27, SNRPE, NSUN2 ZDHHC20 1814/4885ZDHHC2 2700/4885ALDH1A1 4104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.