Sugi Predict

Sugi Predict / Compounds / SCHEMBL35903

SCHEMBL35903

SCHEMBL35903

C=CC(=O)NCCCCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ZDHHC20 Q5W0Z9 1/20 0.60
▸ ZDHHC2 Q9UIJ5 1/20 0.60
▸ PRMT1 Q99873 1/20 0.57
▸ ADRA1A P35348 1/20 0.53
▸ MAPK1 P28482 2/20 0.48
▸ TSHR P16473 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ ABCC4 O15439 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ TGM2 P21980 1/20 0.46
▸ LMNA P02545 2/20 0.46
▸ EPHX2 P34913 6/20 0.45
▸ PLA2G2A P14555 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16229524 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1332462 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL15463341 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1334526 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018094 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1015381 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018444 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL707155 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1083120 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1
SCHEMBL1018405 0.98 ZDHHC20 (0.63) ZDHHC20ZDHHC2PRMT1ADRA1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2705390-B9 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2025-01-22 — — EP claimed
CN-116829675-B Inversion surfactant for inverse emulsion 能源解决方案(美国)有限责任公司 2024-12-10 — — CN claimed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 — — US claimed
EP-2705390-B2 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE (US) 2023-11-15 — — EP claimed
CN-116829675-A Inversion surfactant for inverse emulsion 能源解决方案(美国)有限责任公司 2023-09-29 — — CN claimed
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 — — CN claimed
EP-4017478-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS Alcon Inc. (CH) 2022-06-29 — — EP claimed
EP-3746820-B1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC (CH) 2022-02-16 — — EP claimed
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 — — US claimed
WO-2021053586-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-25 — — WO claimed
WO-2013177523-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 — — WO claimed
US-20130317131-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 — — US claimed
WO-2013176886-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 — — WO claimed
US-20130217620-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-08-22 — — US claimed
US-20130203813-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-08-08 — — US claimed
US-20130203812-A1 IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NUTRICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-08-08 — — US claimed
US-20130168617-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 — — US claimed
WO-2013096604-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 — — WO claimed
US-20120283353-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. 2012-11-08 — — US claimed
WO-2012151135-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2012-11-08 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203812-A1 IONIC SILICONE HYDROGELS COMPRISING PHARMACEUTICAL AND/OR NUTRICEUTICAL COMPONENTS AND HAVING IMPROVED HYDROLYTIC STABILITY IGFBP6, IGFBP1, IGFBP2 ZDHHC20 3675/4885ZDHHC2 3695/4885PRMT1 871/4885
US-20130217620-A1 IONIC SILICONE HYDROGELS HACD2, IGFBP2, IGFBP6 ZDHHC20 3825/4885ZDHHC2 3836/4885PRMT1 820/4885
US-20130203813-A1 MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME LCT, CEL, PIGS ZDHHC20 2700/4885ZDHHC2 2268/4885PRMT1 420/4885
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 ZDHHC20 2735/4885ZDHHC2 3795/4885PRMT1 4468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.