Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876662 | 0.87 | HSD11B1 (0.60) | ALDH1A1PKMCYP19A1NPY5RHTT | |
| SCHEMBL3872680 | 0.87 | ALDH1A1 (0.64) | ALDH1A1PKMHTTMEN1KMT2A | |
| SCHEMBL3878132 | 0.83 | HTT (0.58) | ALDH1A1PKMHTTMEN1KMT2A | |
| SCHEMBL3873253 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PKMNPY5RHTTF10 | |
| SCHEMBL3874725 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PKMCYP19A1HTTMEN1 | |
| SCHEMBL3872817 | 0.80 | HTT (0.68) | CYP19A1HTTF2F10POLB | |
| SCHEMBL23052424 | 0.79 | NPY5R (0.69) | ALDH1A1CYP19A1NPY5RKMT2AACACB | |
| SCHEMBL3872261 | 0.77 | ALDH1A1 (0.56) | ALDH1A1PKMHTTMEN1KMT2A | |
| SCHEMBL3871576 | 0.76 | POLB (0.78) | ALDH1A1CYP19A1NPY5RF2F10 | |
| SCHEMBL3882407 | 0.76 | GPR17 (0.64) | ALDH1A1CYP19A1F2F10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | ALDH1A1 210/4885PKM 1568/4885CYP19A1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.