Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698703 | 0.84 | AGTR1 (0.47) | ALDH1A1LMNASMN1; SMN2KCNN4AGTR1 | |
| SCHEMBL3838617 | 0.83 | AGTR1 (0.41) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13369361 | 0.81 | AGTR1 (0.39) | ALDH1A1LMNASMN1; SMN2P2RX7KCNN4 | |
| SCHEMBL2447241 | 0.81 | KCNN4 (0.43) | ALDH1A1LMNASMN1; SMN2HSD11B1P2RX7 | |
| SCHEMBL9272605 | 0.80 | KCNN4 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL635 | 0.79 | AGTR1 (0.51) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL30956037 | 0.79 | AGTR1 (0.51) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1196906 | 0.79 | HSD11B1 (0.38) | ALDH1A1LMNAHSD11B1AGTR1AGTR2 | |
| SCHEMBL29792716 | 0.79 | HSD11B1 (0.38) | ALDH1A1LMNAHSD11B1AGTR1AGTR2 | |
| SCHEMBL976147 | 0.78 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2HSD11B1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833801-B9 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2009-02-25 | — | — | EP | disclosed |
| EP-1833801-B1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF ANGIOTENSIN II RECEPTOR ANTAGONISTS | ALGRY QUIMICA S L (ES) | 2008-06-04 | — | — | EP | disclosed |