Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 9/20 | 0.40 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL8696833 | 0.94 | BHMT (0.40) | BHMTBHMT2RNPEPMETAP2METAP1 | |
| SCHEMBL7263576 | 0.89 | RNPEP (0.37) | BHMTBHMT2RNPEPMETAP2METAP1 | |
| Methionine SCHEMBL3883236 | 0.88 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27559551 | 0.88 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL3239125 | 0.88 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Homoserine SCHEMBL18893705 | 0.86 | BHMT (0.42) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Serine SCHEMBL3442575 | 0.85 | GSR (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Serine SCHEMBL5577056 | 0.84 | RNPEP (0.37) | BHMTBHMT2RNPEPMETAP2METAP1 | |
| SCHEMBL9755602 | 0.83 | BHMT (0.34) | BHMTBHMT2RNPEPMETAP2METAP1 | |
| SCHEMBL2804079 | 0.82 | METAP2 (0.40) | BHMTBHMT2RNPEPMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002869-B1 | A chemically synthesised artificial promotor for high level expression of transgenes and a method for its synthesis | COUNCIL SCIENT IND RES (IN) | 2009-01-07 | — | — | EP | claimed |
| EP-1002869-A1 | A chemically synthesised artificial promotor for high level expression of transgenes and a method for its synthesis | Council of Scientific and Industrial Research (IN) | 2000-05-24 | — | — | EP | claimed |