Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889224 | 0.99 | MAT2A (0.39) | MAT2AADRB1ADRB3GRM2KMO | |
| SCHEMBL3881975 | 0.92 | SCD5 (0.39) | MAT2AADRB1ADRB3GRM2KMO | |
| SCHEMBL3882431 | 0.89 | ADRB1 (0.36) | ADRB1ADRB3GRM2KMOTPH1 | |
| SCHEMBL3882307 | 0.86 | FFAR4 (0.46) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3881161 | 0.85 | FFAR4 (0.46) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3897875 | 0.82 | ITGB1 (0.42) | ADRB1ADRB3GRM2ITGB1ITGA4 | |
| SCHEMBL3881678 | 0.82 | HRH3 (0.40) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3887129 | 0.82 | ADRB1 (0.44) | ADRB1ADRB3KMOTPH1ITGB1 | |
| SCHEMBL3890185 | 0.82 | TPH1 (0.37) | ADRB1ADRB3GRM2KMOTPH1 | |
| SCHEMBL3888282 | 0.82 | GRM2 (0.39) | ADRB1ADRB3GRM2KMOTPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |