Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | ATM | Q13315 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30350015 | 1.00 | MEN1 (0.74) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| Bromide SCHEMBL5940986 | 0.99 | MEN1 (0.73) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL25443888 | 0.90 | MEN1 (0.78) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL12651748 | 0.87 | MEN1 (0.74) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL51872 | 0.87 | MEN1 (0.82) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL8592677 | 0.86 | ALDH1A1 (0.77) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL28843732 | 0.86 | MEN1 (0.77) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL42693 | 0.85 | ALDH1A1 (1.00) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL29775307 | 0.85 | ALDH1A1 (1.00) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL1131018 | 0.85 | MEN1 (1.00) | MEN1MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693091-B2 | CONTAINING PHOTOACTIVE, FLUORESCENT, OR RADIOACTIVE MOIETY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2004-02-17 | — | — | US | claimed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | claimed |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | THE TRUSTEES OF COLUMBIA UNIVERSITY | 2003-10-16 | — | — | US | claimed |
| WO-2003082185-A2 | ANALOGS OF TERPENE TRILACTONES FROM GINKGO BILOBA AND RELATED COMPOUNDS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-10-09 | — | — | WO | claimed |
| CN-115867544-A | Substituted coumarin dyes and their use as fluorescent labels | 伊鲁米纳剑桥有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20130287700-A1 | COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM | KLINIKUM DARMSTADT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-06-18 | — | — | US | disclosed |
| US-7541368-B2 | 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-{3-[1-(1-methyl-cyclopropanecarbonyl)-piperidin-4-ylmethyl]-phenyl}-urea; use in the treatment of disease states capable of being modulated by the inhibition of p38 kinase and tumor necrosis factor (TNF) | AVENTIS PHARMACEUTICALS INC. (US) | 2009-06-02 | — | — | US | disclosed |
| EP-1117838-B1 | A METHOD FOR ANALYZING POLYNUCLEOTIDES | VARIAGENICS INC (US) | 2009-05-13 | — | — | EP | disclosed |
| US-7473788-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-01-06 | — | — | US | disclosed |
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-05-03 | — | — | US | disclosed |
| EP-1117838-A4 | A METHOD FOR ANALYZING POLYNUCLEOTIDES | VARIAGENICS INC (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20030087398-A1 | Method for analyzing polynucleotides | NUVELO, INC. | 2003-05-08 | — | — | US | disclosed |
| US-6500650-B1 | Method for identifying polymorphisms | VARIAGENICS, INC. | 2002-12-31 | — | — | US | disclosed |
| US-20020150943-A1 | Genotyping by mass spectrometric analysis of allelic fragments | VARIAGENICS, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6458945-B1 | DETECTING VARIANCE IN NUCLEOTIDE SEQUENCE; MIXING ADENOSINE-CYTOSINE-, THYMIDINE-, OR URIDINE TRIPHOSPHATE WITH NUCLEOTIDE IN PRESENCE OF POLYMERASE | VARIAGENICS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6440705-B1 | DETECTION OF VARIANCE IN NUCLEOTIDE SEQUENCE WITHOUT THE NEED FOR FULL SEQUENCE DETERMINATION; GENOTYPING AND LABELING WHILE CLEAVING DNA STRANDS; ELECTROPHORESIS | NUVELO, INC. | 2002-08-27 | — | — | US | disclosed |
| WO-2002021098-A2 | A METHOD FOR IDENTIFYING POLYMORPHISMS | VARIAGENICS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-1117838-A1 | A METHOD FOR ANALYZING POLYNUCLEOTIDES | Variagenics, Inc. (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018967-A1 | A METHOD FOR ANALYZING POLYNUCLEOTIDES | VARIAGENICS, INC. (US) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | GRK5, GPR55, GPBAR1 | MEN1 3188/4885MAPT 4742/4885KMT2A 4407/4885 |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | GPBAR1, GRK5, CNR1 | MEN1 3812/4885MAPT 4801/4885KMT2A 4521/4885 |
| US-20090156668-A1 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof | PYGB, NLN, GRIN3B | MEN1 249/4885MAPT 39/4885KMT2A 4301/4885 |
| US-20130287700-A1 | COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM | SNCA, MAPT, TARDBP | MEN1 2209/4885MAPT 2/4885KMT2A 4298/4885 |
| US-20030087398-A1 | Method for analyzing polynucleotides | POLN, POLRMT, POLM | MEN1 3272/4885MAPT 3174/4885KMT2A 3548/4885 |
| US-20030194370-A1 | Analogs of terpene trilactones from ginkgo biloba for bioorganic and imaging studies | GRK4, GRK1, GNB1 | MEN1 2708/4885MAPT 4042/4885KMT2A 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.