Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 15/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118643 | 0.74 | PDGFRB (0.62) | PDGFRBPDGFRAEGFRINSRLCK | |
| SCHEMBL24614203 | 0.70 | PDGFRB (0.60) | PDGFRBPDGFRAEGFRINSRLCK | |
| SCHEMBL8886903 | 0.69 | IDO1 (0.39) | IDO1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL30605581 | 0.68 | ALDH1A1 (0.47) | PDGFRBPDGFRAEGFRPGK1ALDH1A1 | |
| SCHEMBL24894766 | 0.68 | PDGFRB (0.59) | PDGFRBPDGFRAEGFRINSRLCK | |
| SCHEMBL3395817 | 0.68 | PDGFRB (0.58) | PDGFRBPDGFRAEGFRINSRLCK | |
| SCHEMBL28296734 | 0.66 | TRPM8 (0.45) | PGK1IDO1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28296733 | 0.66 | TRPM8 (0.45) | PGK1IDO1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12844007 | 0.65 | ALDH1A1 (0.50) | PDGFRBPDGFRAEGFRINSRLCK | |
| SCHEMBL3909786 | 0.64 | PDGFRB (1.00) | PDGFRBPDGFRAEGFRLCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687642-B1 | Screening methods for combinations of biological compounds | CENTELION (FR) | 2009-01-14 | — | — | EP | disclosed |