Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549777 | 1.00 | PLA2G2C (0.47) | PLA2G2CGPR84FFAR1LMNAMEN1 | |
| SCHEMBL3888142 | 1.00 | PLA2G2C (0.47) | PLA2G2CGPR84FFAR1LMNAMEN1 | |
| SCHEMBL11050261 | 1.00 | PLA2G2C (0.47) | PLA2G2CGPR84FFAR1LMNAMEN1 | |
| SCHEMBL7639204 | 1.00 | PLA2G2C (0.47) | PLA2G2CGPR84FFAR1LMNAMEN1 | |
| SCHEMBL4820666 | 0.92 | PLA2G2C (0.46) | PLA2G2CMEN1KMT2AASAH1PLA2G10 | |
| SCHEMBL16762206 | 0.92 | PLA2G2C (0.46) | PLA2G2CMEN1KMT2AASAH1PLA2G10 | |
| SCHEMBL4820679 | 0.92 | PLA2G2C (0.46) | PLA2G2CMEN1KMT2AASAH1PLA2G10 | |
| SCHEMBL20459227 | 0.90 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL20459159 | 0.90 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK | |
| SCHEMBL5012513 | 0.90 | PLA2G2C (0.56) | PLA2G2CGPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565179-B1 | COMPOSITION COMPRISING A CARBAMIC ACID DERIVATIVE, ITS USE AS COSMETIC AND MEDICINE | EXPANSCIENCE LAB (FR) | 2009-01-14 | — | — | EP | claimed |
| US-8653117-B2 | Composition comprising at least one oxazoline to inhibit migration of langerhans cells, and uses thereof | LABORATOIRES EXPANSCIENCE (FR) | 2014-02-18 | — | — | US | disclosed |
| US-8304453-B2 | Composition comprising at least one alkanolamide to inhibit migration of langerhans cells and uses therof | LABORATOIRES EXPANSCIENCE (FR) | 2012-11-06 | — | — | US | disclosed |
| US-8236836-B2 | Antiinflammatory agents, soothing agents, enzyme inhibitors, chelate compounds or alkanolamides using oxazoline derivatives | LABORATOIRES EXPANSCIENCE (FR) | 2012-08-07 | — | — | US | disclosed |
| CN-1617704-B | Composition comprising at least one oxazolin for inhibiting langerhans cell migration, and uses thereof | EXPANSCIENCE LAB | 2011-10-05 | — | — | CN | disclosed |
| CN-1617703-B | Composition comprising at least one alkanolamide for inhibiting Langerhans cell migration and uses thereof | EXPANSCIENCE LAB | 2010-12-01 | — | — | CN | disclosed |
| US-20090137453-A1 | COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE TO INHIBIT MIGRATION OF LANGERHANS CELLS, AND USES THEREOF | MSIKA PHILIPPE | 2009-05-28 | — | — | US | disclosed |
| US-20060194881-A1 | Composition comprising at least one alkanolamide to inhibit megration of langerhans cells and uses therof | MSIKA PHILIPPE | 2006-08-31 | — | — | US | disclosed |
| CN-1617703-A | Composition comprising at least one alkanolamide for inhibiting Langerhans cell migration and uses thereof | EXPANSCIENCE LAB (FR) | 2005-05-18 | — | — | CN | disclosed |
| CN-1617704-A | Composition comprising at least one oxazolin for inhibiting langerhans cell migration, and uses thereof | EXPANSCIENCE LAB (FR) | 2005-05-18 | — | — | CN | disclosed |
| US-20050075380-A1 | Composition comprising at least one oxazolin for inhibiting langerhans cell migratio, and uses thereof | LABORATOIRES EXPANSCIENCE (FR) | 2005-04-07 | — | — | US | disclosed |
| US-20050075397-A1 | Composition comprising at least one alkanolamide for inhibiting langerhans cells migration, and uses thereof | LABORATOIRES EXPANSCIENCE (FR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075397-A1 | Composition comprising at least one alkanolamide for inhibiting langerhans cells migration, and uses thereof | ARG1, CPA3, MIF | PLA2G2C 2686/4885GPR84 534/4885FFAR1 1100/4885 |
| US-20090137453-A1 | COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE TO INHIBIT MIGRATION OF LANGERHANS CELLS, AND USES THEREOF | ARG1, MIF, ZAP70 | PLA2G2C 2760/4885GPR84 654/4885FFAR1 1409/4885 |
| US-20050075380-A1 | Composition comprising at least one oxazolin for inhibiting langerhans cell migratio, and uses thereof | MIF, CUTA, ARG1 | PLA2G2C 1696/4885GPR84 958/4885FFAR1 1205/4885 |
| US-20060194881-A1 | Composition comprising at least one alkanolamide to inhibit megration of langerhans cells and uses therof | TPSG1, CPA3, CTSF | PLA2G2C 3839/4885GPR84 303/4885FFAR1 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.