Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | TPH1 | P17752 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.34 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.34 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881912 | 0.84 | S1PR1 (0.49) | S1PR1S1PR3S1PR5FFAR4 | |
| SCHEMBL3892376 | 0.83 | PDE4A (0.43) | TPH1S1PR5ADRB1ADRB3PDE4A | |
| SCHEMBL3884512 | 0.83 | IKBKB (0.44) | ADRB1ADRB3KMOPDE4AFFAR4 | |
| SCHEMBL3891048 | 0.83 | MAPK14 (0.41) | S1PR1TPH1S1PR3 | |
| SCHEMBL3887129 | 0.82 | ADRB1 (0.44) | TPH1S1PR5ADRB1ADRB3KMO | |
| SCHEMBL3893626 | 0.82 | IKBKB (0.43) | ADRB1ADRB3KMOPDE4AFFAR4 | |
| SCHEMBL3881923 | 0.82 | MAPK14 (0.40) | TPH1ADRB1ADRB3KMO | |
| SCHEMBL3890185 | 0.82 | TPH1 (0.37) | S1PR1TPH1S1PR3S1PR5ADRB1 | |
| SCHEMBL3889253 | 0.82 | MAPK14 (0.40) | TPH1ADRB1ADRB3KMO | |
| SCHEMBL3883750 | 0.82 | S1PR1 (0.42) | S1PR1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |