Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222333 | 0.84 | MAOB (0.52) | MAOBACHEALDH1A1 | |
| SCHEMBL4592504 | 0.76 | MAOB (0.49) | MAOBACHEALDH1A1MAPT | |
| SCHEMBL219546 | 0.76 | MAOB (0.51) | MAOBACHE | |
| SCHEMBL3885138 | 0.73 | HTR4 (0.33) | HTR4ALDH1A1PKMENPP1 | |
| SCHEMBL4592501 | 0.73 | MAOB (0.48) | MAOBACHEALDH1A1MAPTPKM | |
| Taltrimide SCHEMBL29866257 | 0.72 | NPSR1 (0.48) | MAOBALDH1A1 | |
| Taltrimide SCHEMBL347001 | 0.72 | NPSR1 (0.48) | MAOBALDH1A1 | |
| SCHEMBL221260 | 0.71 | MAOB (0.46) | MAOBACHE | |
| SCHEMBL3757316 | 0.70 | GLS (0.49) | — | |
| SCHEMBL18605556 | 0.70 | GLS (0.42) | MAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |