SCHEMBL3885449

SCHEMBL3885449

CCCCCCCC(=O)[C]=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.56
CES1 P23141 4/20 0.56
GPR84 Q9NQS5 7/20 0.54
PPARG P37231 7/20 0.54
PPARD Q03181 7/20 0.54
PPARA Q07869 7/20 0.54
HDAC11 Q96DB2 5/20 0.54
TSHR P16473 5/20 0.54
PTPN1 P18031 3/20 0.54
ALDH1A1 P00352 3/20 0.54
TLR2 O60603 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
FABP4 P15090 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SLC22A8 Q8TCC7 1/20 0.54
MEN1 O00255 1/20 0.54
ESR1 P03372 1/20 0.54
ALOX15 P16050 1/20 0.54
PDE4A P27815 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27839324 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL28614140 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL16100284 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL8443919 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL1562757 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL3172758 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL10530967 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL6536571 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL3134715 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD
SCHEMBL28192658 1.00 CES2 (0.56) CES2CES1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3313370-B1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION CONTIPRO AS (CZ) 2020-12-30 EP claimed
US-20180296473-A1 Ophthalmologic Pharmaceutical Composition CONTIPRO A.S. (CZ) 2018-10-18 US claimed
EP-3313370-A1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION Contipro A.S. (CZ) 2018-05-02 EP claimed
WO-2016207340-A1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION TRB CHEMEDICA AG (DE) 2016-12-29 WO claimed
EP-3108874-A1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION TRB Chemedica AG (DE) 2016-12-28 EP claimed
CN-113376965-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376962-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376963-B Coloring composition and compound 住友化学株式会社 2024-05-28 CN disclosed
CN-113376964-B Coloring composition and compound 住友化学株式会社 2024-04-26 CN disclosed
CN-107797382-B Coloring composition 住友化学株式会社 2022-02-22 CN disclosed
CN-107797381-B Coloring composition and compound 住友化学株式会社 2022-02-18 CN disclosed
CN-113376962-A Coloring composition and compound 住友化学株式会社 2021-09-10 CN disclosed
CN-107797382-A Coloured composition 住友化学株式会社 2018-03-13 CN disclosed
CN-107586469-A Color compositions, coloured composition and cured composition for color 住友化学株式会社 2018-01-16 CN disclosed
WO-2016207340-A1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION TRB CHEMEDICA AG (DE) 2016-12-29 WO disclosed
EP-3108874-A1 OPHTHALMOLOGIC PHARMACEUTICAL COMPOSITION TRB Chemedica AG (DE) 2016-12-28 EP disclosed
US-20090240044-A1 PROCESS FOR THE REDUCTION OF ENDOTOXINS IN A PLASMID PREPARATION USING A CARBOHYDRATE NON-IONIC DETERGENT WITH SILICA CHROMATOGRAPHY SIGMA-ALDRICH COMPANY (US) 2009-09-24 US disclosed
US-7531308-B2 Process for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography SIGMA-ALDRICH CO. (US) 2009-05-12 US disclosed
WO-2005111059-A2 PROCESS FOR THE REDUCTION OF ENDOTOXINS SIGMA-ALDRICH CO. (US) 2005-11-24 WO disclosed
US-20050245733-A1 Process for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography SIGMA-ALDRICH CO. 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240044-A1 PROCESS FOR THE REDUCTION OF ENDOTOXINS IN A PLASMID PREPARATION USING A CARBOHYDRATE NON-IONIC DETERGENT WITH SILICA CHROMATOGRAPHY SI, DDOST, LITAF CES2 2658/4885CES1 806/4885GPR84 3971/4885
US-20180296473-A1 Ophthalmologic Pharmaceutical Composition UACA, MYOC, WDR36 CES2 4744/4885CES1 1331/4885GPR84 3247/4885
US-20050245733-A1 Process for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography SI, DDOST, LITAF CES2 2658/4885CES1 806/4885GPR84 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.