Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886809 | 0.92 | PTGS2 (0.42) | PPARAPPARDPTGS2PPARGP2RX3 | |
| SCHEMBL3884645 | 0.92 | PTGS2 (0.43) | PPARAPPARDPTGS2PPARGCHRNB4 | |
| SCHEMBL3891560 | 0.90 | PTGER1 (0.44) | PPARAPTGS2PPARGP2RX3ENPP2 | |
| SCHEMBL3882300 | 0.88 | PTGS2 (0.45) | PPARAPPARDPTGS2PPARGCHRNB4 | |
| SCHEMBL3889372 | 0.87 | PPARD (0.44) | PPARAPPARDPTGS2PPARGENPP2 | |
| SCHEMBL3885377 | 0.86 | CHRNB4 (0.42) | PPARAPPARDPTGS2PPARGCHRNB4 | |
| SCHEMBL3883391 | 0.85 | PTGS2 (0.41) | PPARAPPARDPTGS2PPARGCHRNB4 | |
| SCHEMBL3891017 | 0.85 | PTGS2 (0.43) | PTGS2P2RX3ENPP2MAP3K11PLA2G10 | |
| SCHEMBL3884148 | 0.85 | ENPP2 (0.39) | PPARAPPARDPTGS2PPARGENPP2 | |
| SCHEMBL3882225 | 0.84 | FFAR1 (0.48) | PPARAPPARGCHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |