Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496084 | 1.00 | ALDH1A1 (0.33) | ALDH1A1APLNRTDP1SCN1ASCN2A | |
| SCHEMBL5142163 | 0.81 | TDP1 (0.34) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL6500424 | 0.81 | TDP1 (0.34) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL3320759 | 0.81 | TDP1 (0.34) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL3320762 | 0.81 | TDP1 (0.34) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL6943505 | 0.71 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL6939096 | 0.66 | TDP1 (0.38) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL9186280 | 0.65 | TDP1 (0.40) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL12620916 | 0.63 | TDP1 (0.36) | ALDH1A1TDP1SCN1ASCN2ASCN3A | |
| SCHEMBL16388973 | 0.63 | TDP1 (0.36) | ALDH1A1TDP1SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334405-B2 | Chiral thiourea compounds and process for enantioselective reduction of ketones | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-12-18 | — | — | US | disclosed |
| US-20090253919-A1 | Chiral thiourea compounds and process for enantioselective reduction of ketones | BOARD OF REGENTS (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253919-A1 | Chiral thiourea compounds and process for enantioselective reduction of ketones | TREH, ADH1A, ADH1C | ALDH1A1 99/4885APLNR 2410/4885TDP1 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.