SCHEMBL3889339

SCHEMBL3889339

CC[Si](CC)(CC)C(C)O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690655 0.73 TSHR (0.37) TSHRHSD17B10TDP1
SCHEMBL4810211 0.71 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL12843370 0.69
SCHEMBL32690645 0.69 TSHR (0.39) TSHR
SCHEMBL7335705 0.67
SCHEMBL23778595 0.67
SCHEMBL5925245 0.64
SCHEMBL8977939 0.64
SCHEMBL8002633 0.64
SCHEMBL2985605 0.64 ALDH1A1 (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085078-A1 NON-AQUEOUS SYNTHESIS OF SILYLCARBONATE SOLVENTS UCHICAGO ARGONNE, LLC (US) 2026-03-26 US disclosed
US-10640526-B2 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-05-05 US disclosed
US-20180319833-A1 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-11-08 US disclosed
EP-3377508-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2018-09-26 EP disclosed
EP-3170832-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2017-05-24 EP disclosed
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
JP-2000146983-A DECOMPOSITION FOR CONTINUOUS C-TERMINAL OF PEPTIDE AND PROTEIN CITY OF HOPE 2000-05-26 JP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
US-5789408-A Antiviral thiazoles PFIZER INC. (US) 1998-08-04 US disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
EP-0714393-A1 THIAZOLES AS ANTIVIRAL PFIZER INC. (US) 1996-06-05 EP disclosed
WO-1995005378-A1 ANTIVIRAL THIAZOLES PFIZER INC. (US) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085078-A1 NON-AQUEOUS SYNTHESIS OF SILYLCARBONATE SOLVENTS TRPV2, TRPV3, TRPM2 TSHR 4110/4885ALDH1A1 3475/4885HSD17B10 1783/4885
US-10640526-B2 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose ST6GAL1, B4GALT1, GALNT6 TSHR 191/4885ALDH1A1 2146/4885HSD17B10 4875/4885
US-20180319833-A1 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose ST6GAL1, B4GALT1, GALNT6 TSHR 191/4885ALDH1A1 2146/4885HSD17B10 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.