Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14234008 | 1.00 | L3MBTL1 (0.43) | L3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL14944927 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL11476566 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL14944929 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL14944947 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL14944941 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL11477779 | 0.85 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL16883361 | 0.84 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL18263599 | 0.84 | LMNA (0.38) | L3MBTL1 | |
| SCHEMBL7147304 | 0.84 | LMNA (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847185-B1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-9144239-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2015-09-29 | — | — | US | disclosed |
| US-20140275171-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2014-09-18 | — | — | US | disclosed |
| US-8785479-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES, LLC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130296375-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2013-11-07 | — | — | US | disclosed |
| EP-1483273-B1 | LIGANDS FOR ASYMMETRIC REACTIONS | SOLVIAS AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| US-7407910-B2 | Ligands for asymmetric reactions | SOLVIAS AG (CH) | 2008-08-05 | — | — | US | disclosed |
| US-20060241307-A1 | Bidentate having a heterocyclic ring, especially benzothiophene, 2,3-disubstituted with phosphonate, phosphine, phosphine oxide, dioxyphosphine or diaminophosphine groups; transition metal complexes; hydrogenation, isomerizatioin, hydroformylation, hydroboration, hydrosilylation or hydrocyanation | BERENS ULRICH | 2006-10-26 | — | — | US | disclosed |
| US-7094907-B2 | Ligands for asymmetric reactions | SOLVIAS AG (CH) | 2006-08-22 | — | — | US | disclosed |
| US-20040260091-A1 | Ligands for asymmetric reactions | SOLVIAS AG (CH) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275171-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, FKBP2, CYP51A1 | L3MBTL1 4418/4885HDAC3 357/4885HDAC1 195/4885 |
| US-20060241307-A1 | Bidentate having a heterocyclic ring, especially benzothiophene, 2,3-disubstituted with phosphonate, phosphine, phosphine oxide, dioxyphosphine or diaminophosphine groups; transition metal complexes; hydrogenation, isomerizatioin, hydroformylation, hydroboration, hydrosilylation or hydrocyanation | NR2E3, WNK2, OXSR1 | L3MBTL1 2378/4885HDAC3 2240/4885HDAC1 2518/4885 |
| US-20040260091-A1 | Ligands for asymmetric reactions | COASY, ICMT, AP2M1 | L3MBTL1 4760/4885HDAC3 3397/4885HDAC1 980/4885 |
| US-20130296375-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, FKBP2, CYP51A1 | L3MBTL1 4418/4885HDAC3 357/4885HDAC1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.