Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769885 | 0.93 | POLB (0.37) | NPC1RAB9AADORA2AADORA1MAPT | |
| SCHEMBL21769571 | 0.91 | SLC6A9 (0.36) | NCOA3MAPT | |
| SCHEMBL21769566 | 0.90 | KMT2A (0.37) | NPC1RAB9AADORA2AADORA1MAPT | |
| Amenamevir SCHEMBL2238614 | 0.89 | HDAC1 (0.37) | NPC1RAB9AADORA2AADORA1MAPT | |
| SCHEMBL22055760 | 0.88 | NPC1 (0.36) | NPC1RAB9AADORA2AADORA1NCOA3 | |
| SCHEMBL21769731 | 0.87 | KMT2A (0.40) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL17923455 | 0.87 | MAPT (0.37) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21769874 | 0.86 | MAPT (0.38) | NPC1RAB9AADORA2AADORA1MAPT | |
| SCHEMBL21769853 | 0.85 | POLB (0.38) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21769573 | 0.85 | POLB (0.39) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263671-B1 | AMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | ASTELLAS PHARMA INC (JP) | 2016-07-20 | — | — | EP | claimed |
| WO-2020109389-A1 | HELICASE PRIMASE INHIBITORS FOR TREATING CANCER IN A COMBINATION THERAPY WITH ONCOLYTIC VIRUSES | INNOVATIVE MOLECULES GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |
| WO-2009123169-A1 | AMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | アステラス製薬株式会社 (JP) | 2009-10-08 | — | — | WO | disclosed |