Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 13/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769885 | 0.93 | POLB (0.37) | MAPT | |
| SCHEMBL3892309 | 0.91 | NPC1 (0.37) | NCOA3MAPT | |
| SCHEMBL2239362 | 0.89 | HDAC1 (0.38) | SLC6A9NCOA3SLC6A5 | |
| SCHEMBL21769740 | 0.88 | L3MBTL1 (0.33) | SLC6A9SLC6A5MAPT | |
| SCHEMBL17923453 | 0.88 | MAPT (0.35) | MAPT | |
| SCHEMBL21769874 | 0.86 | MAPT (0.38) | MAPT | |
| SCHEMBL6011885 | 0.86 | NCOA3 (0.31) | SLC6A9NCOA3MAPTIDO1 | |
| SCHEMBL21769850 | 0.86 | HCRTR1 (0.35) | SLC6A9MAPT | |
| SCHEMBL21769853 | 0.86 | POLB (0.38) | MAPT | |
| SCHEMBL21769566 | 0.85 | KMT2A (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |